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2-METHYL-4-OXO-4-(4'-FLUOROPHENYL)BUTYRIC ACID synthesis

3synthesis methods
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Yield:68415-18-9 85%

Reaction Conditions:

with hydrogen;palladium diacetate;zinc trifluoromethanesulfonate;1,4-di(diphenylphosphino)-butane in 1,2-dichloro-ethane at 60; under 750.075 Torr; for 48 h;Autoclave;chemoselective reaction;

References:

Zhang, Xuexin;Gao, Yang;Laishram, Ronibala Devi;Li, Kangkui;Yang, Yong;Zhan, Yong;Luo, Yang;Fan, Baomin [Organic and Biomolecular Chemistry,2019,vol. 17,# 8,p. 2174 - 2181]