2-METHYLTHIO-trans-ZEATIN RIBOSIDE (2MeSZR) synthesis

5synthesis methods

Product Name:2-METHYLTHIO-trans-ZEATIN RIBOSIDE (2MeSZR)
CAS Number:53274-45-6
Molecular formula:C16H23N5O5S
Molecular Weight:397.45

26728-58-5 Synthesis

26728-58-5
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2-METHYLTHIO-trans-ZEATIN RIBOSIDE (2MeSZR)

53274-45-6
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium carbonate / butan-1-ol / 5 h / 110 °C
2: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 18 h / Reflux
3: sodium methylate; methanol / 6 h / 20 °C
4: Salmonella typhimurium O₂-dependent tRNA modifying monooxgenase; dihydrogen peroxide / dimethyl sulfoxide / 1 h / 27 °C / pH 8 / Enzymatic reaction

References:

Corder, Andra L.;Subedi, Bishnu P.;Zhang, Siai;Dark, Amanda M.;Foss Jr., Frank W.;Pierce, Brad S. [Biochemistry,2013,vol. 52,# 36,p. 6182 - 6196]