2-phenyl-N-(pyridin-4-ylmethyl)ethanamine synthesis
1synthesis methods
- Product Name:2-phenyl-N-(pyridin-4-ylmethyl)ethanamine
- CAS Number:5713-84-8
- Molecular formula:C14H16N2
- Molecular Weight:212.29
Yield:5713-84-8 80%
Reaction Conditions:
Stage #1: pyridine-4-carbaldehyde;phenethylamine in methanol at 20; for 6 h;Inert atmosphere;Reflux;
Stage #2: with sodium tetrahydroborate in methanol; for 2 h;Inert atmosphere;
References:
Lockyer, Selena J.;Fielding, Alistair J.;Whitehead, George F. S.;Timco, Grigore A.;Winpenny, Richard E. P.;McInnes, Eric J. L. [Journal of the American Chemical Society,2019,vol. 141,# 37,p. 14633 - 14642] Location in patent:supporting information