ChemicalBook CAS DataBase List 2-PHENYLIMIDAZO[1,2-A]PYRIMIDINE

2-PHENYLIMIDAZO[1,2-A]PYRIMIDINE synthesis

10synthesis methods

Product Name:2-PHENYLIMIDAZO[1,2-A]PYRIMIDINE
CAS Number:15764-47-3
Molecular formula:C12H9N3
Molecular Weight:195.22

109-12-6
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70-11-1
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$10.00/25g

15764-47-3
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$45.00/10mg

Yield:15764-47-3 90%

Reaction Conditions:

in propan-2-one; for 5 h;Reflux;

Steps:

13 Preparation of compound LA93:

10.0g (0.105mol) of 2-aminopyrimidine and 21.0g (0.105mol) of 2-bromo-1-phenylethanone were mixed, 150mL of acetone was added, and the reaction was stirred at reflux at elevated temperature for 5 hours, cooled to room temperature, filtered, and filtered The cake was washed with acetone, and the obtained solid was dissolved in 200 mL of 3N dilute hydrochloric acid. The temperature was heated and refluxed and stirred for 1 hour. 15% dilute ammonia was added dropwise to adjust to pH-8, cooled to room temperature, filtered, and the filter cake was recrystallized with ethanol to obtain Compound LA93, white solid, yield 90%.

References:

CN113201027,2021,A Location in patent:Paragraph 0159-0163

109-12-6
431 suppliers
$6.00/10g

98-86-2 Synthesis