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ChemicalBook CAS DataBase List 2-(PHENYLSULFONYL)-3-(3-PYRIDYL)PROP-2-ENENITRILE
669708-39-8

2-(PHENYLSULFONYL)-3-(3-PYRIDYL)PROP-2-ENENITRILE synthesis

1synthesis methods
500-22-1 Synthesis
3-Pyridinecarboxaldehyde

500-22-1
485 suppliers
$6.00/5g

7605-28-9 Synthesis
(PHENYLSULFONYL)ACETONITRILE

7605-28-9
145 suppliers
$7.00/1g

2-(PHENYLSULFONYL)-3-(3-PYRIDYL)PROP-2-ENENITRILE

669708-39-8
8 suppliers
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Yield:669708-39-8 70%

Reaction Conditions:

with piperidine;acetic acid in toluene; for 24 h;Reflux;Dean-Stark;

References:

Rajkumar, Sundaram;Shankland, Kenneth;Goodman, Jonathan M.;Cobb, Alexander J. A. [Organic Letters,2013,vol. 15,# 6,p. 1386 - 1389] Location in patent:supporting information