ChemicalBook CAS DataBase List 2-PROPANOL-1,1,1,3,3,3-D6

2-PROPANOL-1,1,1,3,3,3-D6 synthesis

3synthesis methods

Product Name:2-PROPANOL-1,1,1,3,3,3-D6
CAS Number:3976-29-2
Molecular formula:C3H2D6O
Molecular Weight:66.13

666-52-4 Synthesis

666-52-4
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$24.00/10g

3976-29-2
33 suppliers
$45.00/100mg

Yield:3976-29-2 100%

Reaction Conditions:

with lithium aluminium tetrahydride in diethylene glycol dimethyl ether at 0 - 20; for 1 h;

Steps:

7.1 Step 1: Example 7b

To a solution of LAH (6.3 g, 165.8 mmol) in diglyme (175 mL) was slowly added Example 7a (25.0 g, 390.6 mmol) at 0°C. After addition, the mixture was allowed to stir from 0°C to r.t. for 1 h. The reaction was quenched by adding glycol slowly at 0°C, and the resulting mixture was distilled directly (atmospheric pressure, low temperature cooling circulator) and the fraction between 79-l05°C was collected to give the desired product Example 7b (25 g, yield 100%) as colorless liquid.

References:

WO2019/240938,2019,A1 Location in patent:Paragraph 00289

666-52-4 Synthesis

666-52-4
142 suppliers
$24.00/10g