2-Propenoic acid, 2-methyl-, 6-hydroxyhexyl ester synthesis
- Product Name:2-Propenoic acid, 2-methyl-, 6-hydroxyhexyl ester
- CAS Number:13092-57-4
- Molecular formula:C10H18O3
- Molecular Weight:186.25
629-11-8
442 suppliers
$6.00/25g
79-41-4
492 suppliers
$14.00/5g
6606-59-3
151 suppliers
$44.00/25g
13092-57-4
9 suppliers
inquiry
Yield:13092-57-4 67.7% ，6606-59-3 15%
Reaction Conditions:
with 2,6-di-tert-butyl-4-methyl-phenol;toluene-4-sulfonic acid at 90; for 5 h;
Steps:
6-Hydroxyhexyl Methacrylate Synthesis: 1,6-Hexanediol (1000.00 g, 8.46 mol, Sigma-Aldrich) was placed in a 1 -liter 3 -neck flask equipped with a mechanical stirrer and a narrow tube blowing dry air into the flask. The solid diol was heated to 900C, at which temperature all the solid melted. With continuous stirring, p-toluenesulfonic acid crystals (18.95 g, 0.11 mol) followed by BHT (2.42 g, 0.011 mol) and methacrylic acid (728.49.02 g, 8.46 mol). Heating at 9O0C with stirring was continued for 5 hours during which time vacuum was applied using tap water aspirator for 5-10 minutes after each half- hour reaction time. The heat was turned off and the reaction mixture was cooled to room temperature. The viscous liquid obtained was washed with 10% aqueous sodium carbonate twice (2 x 240 ml), followed by washing with water (2 x 240 ml), and finally with 100 ml of saturated NaCl aqueous solution. The obtained oil was dried using anhydrous Na2SO4 EPO
References:
WO2006/55317,2006,A1 Location in patent:Page/Page column 30-31
629-11-8
442 suppliers
$6.00/25g
80-62-6
591 suppliers
$21.00/25mL
6606-59-3
151 suppliers
$44.00/25g
13092-57-4
9 suppliers
inquiry