ChemicalBook CAS DataBase List 2-Propynenitrile, 3-phenyl- (9CI)

2-Propynenitrile, 3-phenyl- (9CI) synthesis

13synthesis methods

Product Name:2-Propynenitrile, 3-phenyl- (9CI)
CAS Number:935-02-4
Molecular formula:C9H5N
Molecular Weight:127.14

78-67-1 Synthesis

78-67-1
401 suppliers
$24.73/1gm:

536-74-3 Synthesis

536-74-3
301 suppliers
$10.00/1g

935-02-4
98 suppliers
$60.00/100mg

Yield: 96%

Reaction Conditions:

with Cu-MOF in acetonitrile at 90; for 9 h;

Steps:

3.1-3.5 Example 3: Cu-MOF catalytic material prepared in Example 2 catalyzed 2,2-azobisisobutyronitrile and phenylacetylene
(1) Benzene acetylene (0.102 g, 1 mmol) and 2,2-azobisisobutyronitrile (0.246 g 1.5 mmol) were weighed in a round bottom flask, and a magnetic charge and a solvent acetonitrile (CH3CN, 5 mL) were added;(2) adding an anionic skeleton Cu-MOF (0.059 g, 0.1 mmol) to the (1) reaction system as a catalyst;(3) then the reaction system (2) is heated at 90 ° C for 9h;(4) After completion of the reaction, it was quenched with water (3), extracted with dichloromethane (DCM) three times, and the organic phase was dried over anhydrous sodium sulfate.Dry, filter, spin dry;(5) Ethyl acetate/petroleum ether was used as a mobile phase, and purified by column chromatography (2), and the isolated yield was 96%.

References:

Zhongyuan University of Technology;Huang Chao;Mi Liwei;Wang Dandan;Wu Jiarui;Zhu Kaifang;Li Gaoxiang;Xu Yupei;Zhang Miaomiao CN109369689, 2019, A Location in patent:Paragraph 0031

1504-58-1 Synthesis