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2-Propynoic acid,3-(2,4-dichlorophenyl)- synthesis

2synthesis methods
-

Yield:6974-65-8 88.8%

Reaction Conditions:

Stage #1: 2,3-dibromo-3-(2,4-dichloro-phenyl)-propionic acidwith potassium tert-butylate in tert-butyl alcohol at 40; for 1.5 h;
Stage #2: with hydrogenchloride in tert-butyl alcohol;

References:

WO2005/63239,2005,A1 Location in patent:Page/Page column 143-144