ChemicalBook CAS DataBase List 2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE

2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE synthesis

5synthesis methods

Product Name:2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE
CAS Number:273408-90-5
Molecular formula:C13H10N4
Molecular Weight:222.25

100-54-9 Synthesis

100-54-9
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$5.00/10g

1885-29-6
441 suppliers
$5.00/1g

273408-90-5
24 suppliers
$356.00/1g

Yield:273408-90-5 86%

Reaction Conditions:

Stage #1: anthranilic acid nitrilewith sodium hydride in tetrahydrofuran at 0;Deprotonation;
Stage #2: pyridine-3-carbonitrile in tetrahydrofuran; for 20 h;Heating;Further stages.;Cycloaddition;

References:

Van Muijlwijk-Koezen, Jacqueline E.;Timmerman, Henk;Van Der Goot, Henk;Menge, Wiro M. P. B.;Von Drabbe Künzel, Jacobien Frijtag;De Groote, Miriam;Ijzerman, Adriaan P. [Journal of Medicinal Chemistry,2000,vol. 43,# 11,p. 2227 - 2238]

500-22-1 Synthesis