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2-Thiazolemethanol, alpha-methyl-, (alphaS)- (9CI) synthesis

1synthesis methods
24295-03-2 Synthesis
2-Acetylthiazole

24295-03-2
382 suppliers
$6.00/5g

2-Thiazolemethanol, alpha-methyl-, (alphaS)- (9CI)

104863-49-2
23 suppliers
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Yield:104863-49-2 94%

Reaction Conditions:

with Triisopropyl borate;potassium tert-butylate;hydrogen;trans-RuCl2[(R)-xylbinap][(R)-daipen] in isopropyl alcohol;tert-butyl alcohol at 25; under 6080.41 Torr; for 12 h;Catalytic hydrogenation;

References:

Ohkuma, Takeshi;Koizumi, Masatoshi;Yoshida, Makoto;Noyori, Ryoji [Organic Letters,2000,vol. 2,# 12,p. 1749 - 1751]