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ChemicalBook CAS DataBase List 2-ThiophenaMine, 5-phenyl-

2-ThiophenaMine, 5-phenyl- synthesis

5synthesis methods
-

Yield:14770-85-5 96%

Reaction Conditions:

Stage #1: 2-phenyl-5-nitrothiophenewith hydrazine hydrate in ethanol at 50; for 0.25 h;
Stage #2: in ethanol;water at 50; for 1 h;

References:

Nguyen, Thuy;Gamage, Thomas F.;Decker, Ann M.;Barrus, Daniel;Langston, Tiffany L.;Li, Jun-Xu;Thomas, Brian F.;Zhang, Yanan [Journal of Medicinal Chemistry,2019,vol. 62,# 21,p. 9806 - 9823]