![](/CAS/GIF/27757-85-3.gif)
2-Thiophenemethylamine synthesis
- Product Name:2-Thiophenemethylamine
- CAS Number:27757-85-3
- Molecular formula:C5H7NS
- Molecular Weight:113.18
![Carbamic acid, (2-thienylmethyl)-, 1,1-dimethylethyl ester (9CI)](/CAS/GIF/401485-19-6.gif)
401485-19-6
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27757-85-3
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$6.00/1g
Yield:27757-85-3 81.5%
Reaction Conditions:
with trifluoroacetic acid in dichloromethane at 20;
Steps:
2.1.2. General Procedure for 3a-3c
General procedure: Compounds 2a-2c (20 mmol) were dissolved in CH2Cl2(200 mL) and TFA (50 mL), and the solution was stirred at room temperature for 3 h. Removal of the solvent resulted in 3a-3c (Scheme 1). 2.1.2.1. Thiophen-2-ylmethanamine(3a)Yield 81.5%; 1H NMR (400MHz, CDCl3) δ: 4.26(s, 2H),7.08 (dd, J 1= 5.2Hz, J2 = 3.6Hz, 1H), 7.23 (d, J =2.8Hz,1H), 7.59 (d, J = 1.2Hz,1H).
References:
Zou, Min;Jin, Bo;Liu, Yanrong;Chen, Huiping;Zhang, Zhuangli;Zhang, Changzheng;Zhao, Zhihong;Zheng, Liyun [Letters in drug design and discovery,2018,vol. 16,# 2,p. 102 - 110]
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98-03-3
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27757-85-3
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129820-44-6
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27757-85-3
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1003-31-2
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27757-85-3
246 suppliers
$6.00/1g