2-(Trifluoromethyl)pyrimidine-4-carBoxamide synthesis
- Product Name:2-(Trifluoromethyl)pyrimidine-4-carBoxamide
- CAS Number:914348-10-0
- Molecular formula:C6H4F3N3O
- Molecular Weight:191.11
878745-51-8
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914348-10-0
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$45.00/50mg
Yield:914348-10-0 99%
Reaction Conditions:
with ammonia in methanol at 50; for 16 h;
Steps:
32.A
Commercially available 2-trifluoromethyl-pyrimidme-4-carboxylic acid methyl ester (1.0 g) was dissolved in a 7M solution OfNH3 in MeOH and heated in a sealed pressure tube to 5O0C for 16 h. Cooling to room temperature and concentration afforded the title compound (941 mg, >99%). [MH]+ = 192.
References:
WO2006/128184,2006,A2 Location in patent:Page/Page column 160
1514-96-1
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914348-10-0
25 suppliers
$45.00/50mg