ChemicalBook CAS DataBase List (2S,3S,3''S)-N-[3-(3-Acetoxy-3-methoxycarbonylpropanamido)-3-tert-butoxythiocarbonylpropanoyl]azetidine-2-thiocarboxylic Acid tert-Butyl Ester

(2S,3S,3''S)-N-[3-(3-Acetoxy-3-methoxycarbonylpropanamido)-3-tert-butoxythiocarbonylpropanoyl]azetidine-2-thiocarboxylic Acid tert-Butyl Ester synthesis

5synthesis methods

Product Name:(2S,3S,3''S)-N-[3-(3-Acetoxy-3-methoxycarbonylpropanamido)-3-tert-butoxythiocarbonylpropanoyl]azetidine-2-thiocarboxylic Acid tert-Butyl Ester
CAS Number:201283-57-0
Molecular formula:C23H36N2O8S2
Molecular Weight:532.67

39701-84-3 Synthesis

METHYL 2-(S)-ACETOXY-3-CARBOXYPROPANOATE

39701-84-3
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(2S,3S,3''S)-N-[3-(3-Acetoxy-3-methoxycarbonylpropanamido)-3-tert-butoxythiocarbonylpropanoyl]azetidine-2-thiocarboxylic Acid tert-Butyl Ester

201283-57-0
11 suppliers
$181.69/1mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 95.3 percent / HOBt; DCC / CH₂Cl₂ / 6 h / 20 °C
2: 96 percent / H₂ / Pd/C / ethyl acetate / 2.5 h / 20 °C
3: 71.2 percent / HOBt; DCC / CH₂Cl₂ / 6 h / 20 °C
4: 94.6 percent / Lawesson's reagent / benzene / 3 h / 80 °C

References:

Miyakoshi, Katsuhiro;Oshita, Jun;Kitahara, Takeshi [Tetrahedron,2001,vol. 57,# 16,p. 3355 - 3360]

201283-56-9 Synthesis