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4-Piperidinol, 4-ethynyl-1-methyl- (6CI, 7CI, 8CI, 9CI) synthesis
1synthesis methods
- Product Name:4-Piperidinol, 4-ethynyl-1-methyl- (6CI, 7CI, 8CI, 9CI)
- CAS Number:20734-46-7
- Molecular formula:C8H13NO
- Molecular Weight:139.19
Yield:20734-46-7 93.8%
Reaction Conditions:
with potassium hydroxide in diethyl ether;ammonia;1.) 6 h, 2.) overnight;
References:
Korablev, M. V.;Praliev, K. D.;Salita, T. A.;Zhilkibaev, O. T.;Kurbat N. M.;et al. [Pharmaceutical Chemistry Journal,1985,vol. 19,# 4,p. 252 - 256][Khimiko-Farmatsevticheskii Zhurnal,1985,vol. 19,# 4,p. 419 - 422]