2-(2,6-dichlorophenyl)-2-(6-(2,4-difluorophenylthio)pyridazin-3-yl)acetonitrile synthesis

2synthesis methods

Product Name:2-(2,6-dichlorophenyl)-2-(6-(2,4-difluorophenylthio)pyridazin-3-yl)acetonitrile
CAS Number:209412-22-6
Molecular formula:C18H9Cl2F2N3S
Molecular Weight:408.25

1996-44-7
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$12.00/1g

2-(6-CHLORO-3-PYRIDAZINYL)-2-(2,6-DICHLOROPHENYL)ACETONITRILE

209412-06-6
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2-(2,6-dichlorophenyl)-2-(6-(2,4-difluorophenylthio)pyridazin-3-yl)acetonitrile

209412-22-6
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Yield:209412-22-6 92%

Reaction Conditions:

with trans-1,2-cyclohexandiol;potassium carbonate in isopropyl alcohol at 120; for 3 h;Microwave irradiation;Ullmann type coupling;

References:

Bagley, Mark C.;Davis, Terence;Dix, Matthew C.;Fusillo, Vincenzo;Pigeaux, Morgane;Rokicki, Michal J.;Kipling, David [Journal of Organic Chemistry,2009,vol. 74,# 21,p. 8336 - 8342] Location in patent:supporting information; experimental part

3215-64-3
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$10.00/5g

209412-22-6
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References