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210579-45-6

Butanoic acid, 2-[(3-nitrophenyl)methylene]-3-oxo-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl ester synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 80 percent / xylene / 8.5 h / Heating
2: 72 percent / toluene / 2 h / 80 °C
3: 91 percent / HCl / CHCl3 / 15 °C

References:

Leonardi, Amedeo;Motta, Gianni;Pennini, Renzo;Testa, Rodolfo;Sironi, Giorgio;Catto, Alberto;Cerri, Alberto;Zappa, Marco;Bianchi, Giorgio;Nardi, Dante [European Journal of Medicinal Chemistry,1998,vol. 33,# 5,p. 399 - 420]