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ChemicalBook CAS DataBase List Benzenepropanoic acid, β-amino-3,5-dichloro-, ethyl ester, hydrochloride (1:1)

Benzenepropanoic acid, β-amino-3,5-dichloro-, ethyl ester, hydrochloride (1:1) synthesis

2synthesis methods
188812-95-5 Synthesis
3-AMINO-3-(3,5-DICHLORO-PHENYL)-PROPIONIC ACID

188812-95-5
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Benzenepropanoic acid, β-amino-3,5-dichloro-, ethyl ester, hydrochloride (1:1)

215738-51-5
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Yield:215738-51-5 90%

Reaction Conditions:

with thionyl chloride at -15;Reflux;Inert atmosphere;

References:

Adams, James;Anderson, Edward C.;Blackham, Emma E.;Chiu, Yin Wa Ryan;Clarke, Thomas;Eccles, Natasha;Gill, Luke A.;Haye, Joshua J.;Haywood, Harvey T.;Hoenig, Christian R.;Kausas, Marius;Le, Joelle;Russell, Hannah L.;Smedley, Christopher;Tipping, William J.;Tongue, Tom;Wood, Charlotte C.;Yeung, Jason;Rowedder, James E.;Fray, M. Jonathan;McInally, Thomas;Macdonald, Simon J. F. [ACS Medicinal Chemistry Letters,2014,vol. 5,# 11,p. 1207 - 1212] Location in patent:supporting information

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