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ChemicalBook CAS DataBase List 1,2,4-Triazolo[3,4-a]phthalazine, 6-chloro-3-(5-Methyl-3-isoxazolyl)-

1,2,4-Triazolo[3,4-a]phthalazine, 6-chloro-3-(5-Methyl-3-isoxazolyl)- synthesis

1synthesis methods
3-Isoxazolecarboxylic acid, 5-methyl-, 2-(4-chloro-1-phthalazinyl)hydrazide

215874-90-1
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1,2,4-Triazolo[3,4-a]phthalazine, 6-chloro-3-(5-Methyl-3-isoxazolyl)-

215874-89-8
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Yield:215874-89-8 58%

Reaction Conditions:

with triethylamine hydrochloride in xylene; for 3 h;Heating;

References:

Sternfeld, Francine;Carling, Robert W.;Jelley, Richard A.;Ladduwahetty, Tamara;Merchant, Kevin J.;Moore, Kevin W.;Reeve, Austin J.;Street, Leslie J.;O'Connor, Desmond;Sohal, Bindi;Atack, John R.;Cook, Susan;Seabrook, Guy;Wafford, Keith;Tattersall, F. David;Collinson, Neil;Dawson, Gerard R.;Castro, José L.;MacLeod, Angus M. [Journal of Medicinal Chemistry,2004,vol. 47,# 9,p. 2176 - 2179]