ChemicalBook CAS DataBase List 4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID

4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID synthesis

1synthesis methods

Product Name:4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
CAS Number:216959-92-1
Molecular formula:C9H7N3O2S
Molecular Weight:221.24

22900-83-0 Synthesis

ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE

22900-83-0
190 suppliers
$5.00/250mg

4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID

216959-92-1
37 suppliers
$90.00/50mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) chloride / N,N-dimethyl-formamide / 0.5 h / 100 °C / Inert atmosphere; Microwave irradiation
2: lithium hydroxide monohydrate; water / tetrahydrofuran / 16 h / 23 °C

References:

WO2015/161928,2015,A1

4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID Related Search:

Thiazole-5-carboxylic acid 4-Methylthiazole-5-carboxylic acid Trimethyl thiazole 2,5-Dimethylthiazole 2-methyl-1,3-thiazole-5-carboxylic acid (2,4-DIMETHYL-1,3-THIAZOL-5-YL)METHANOL 5-Hydroxymethylthiazole 4-Methylthiazole-5-carboxaldehyde 2,4-Dimethylthiazole-5-carboxylic acid