ChemicalBook CAS DataBase List 4-Thiazolecarboxylic acid, 2-(hydroxymethyl)- (9CI)

4-Thiazolecarboxylic acid, 2-(hydroxymethyl)- (9CI) synthesis

5synthesis methods

Product Name:4-Thiazolecarboxylic acid, 2-(hydroxymethyl)- (9CI)
CAS Number:221322-09-4
Molecular formula:C5H5NO3S
Molecular Weight:159.16

2-(2,2-DIMETHYL-PROPIONYLOXYMETHYL)-THIAZOLE-4-CARBOXYLIC ACID

221322-07-2
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4-Thiazolecarboxylic acid, 2-(hydroxymethyl)- (9CI)

221322-09-4
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Yield:221322-09-4 86%

Reaction Conditions:

with potassium carbonate in methanol;water; for 4.5 h;Heating;

References:

Macdonald, Simon J. F.;Dowle, Michael D.;Harrison, Lee A.;Clarke, Geoffrey D. E.;Inglis, Graham G. A.;Johnson, Martin R.;Shah, Pritom;Smith, Robin A.;Amour, Augustin;Fleetwood, Gill;Humphreys, Davina C.;Molloy, Christopher R.;Dixon, Mary;Godward, Rosalind E.;Wonacott, Alan J.;Singh, Onkar M. P.;Hodgson, Simon T.;Hardy, George W. [Journal of Medicinal Chemistry,2002,vol. 45,# 18,p. 3878 - 3890]

4-Thiazolecarboxylic acid, 2-[(2,2-dimethyl-1-oxopropoxy)methyl]-, ethyl ester

1197023-27-0
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221322-09-4
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References

6436-59-5 Synthesis

6436-59-5
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$9.00/1g

221322-09-4
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References

73956-17-9
72 suppliers
$11.00/100mg

221322-09-4
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References

40235-65-2 Synthesis

Ethyl 2-(hydroxyMethyl)thiazole-4-carboxylate

40235-65-2
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221322-09-4
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References