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benzoic acid, 4-(2-oxo-1-pyrrolidinyl)-, methyl ester synthesis

8synthesis methods
-

Yield:221381-89-1 98%

Reaction Conditions:

with tris(1,5-diphenylpenta-1,4-dien-3-one)dipalladium;Cs2CO3;4,5-bis(diphenylphosphino)-9,9-dimethylxanthene in 1,4-dioxane at 90; for 2 h;Inert atmosphere;Buchwald-Hartwig Coupling;

References:

Cho, Er-Chieh;Liu, Chi-Yuan;Tang, Di-Wei;Lee, Hsueh-Yun [Journal of Enzyme Inhibition and Medicinal Chemistry,2021,vol. 36,# 1,p. 1387 - 1401]