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222412-75-1

2-[2-(4-fluorophenyl)-2-oxo-1-(2,3,4,5,6-pentadeuteriophenyl)ethyl]-4-methyl-3-oxo-N-phenylpentanamide synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.1 g / β-alanine; acetic acid / hexane / 28 h / Heating
2: 55 percent / 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / 13 h / 60 - 71 °C

References:

Woo, Peter W. K.;Hartman, Jon;Hicks, James;Hayes, Roger [Journal of labelled compounds and radiopharmaceuticals,1999,vol. 42,# 2,p. 135 - 145]