Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate synthesis

3synthesis methods

Product Name:Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate
CAS Number:223388-20-3
Molecular formula:C11H8ClNO3
Molecular Weight:237.64

13972-97-9 Synthesis

3-Isoquinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-1-oxo-, Methyl ester

13972-97-9
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Methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate

223388-20-3
16 suppliers
$45.00/100mg

Yield:223388-20-3 98%

Reaction Conditions:

with trichlorophosphate at 80; for 2 h;

References:

Stubbs, Christopher J.;Loenarz, Christoph;Mecinovi?, Jasmin;Kar, Kheng Yeoh;Hindley, Nicola;Liénard, Beno?t M.;Sobott, Frank;Schofield, Christopher J.;Flashman, Emily [Journal of Medicinal Chemistry,2009,vol. 52,# 9,p. 2799 - 2805] Location in patent:supporting information; experimental part

13972-97-9 Synthesis

13972-97-9
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223388-20-3
16 suppliers
$45.00/100mg

References

3-CARBOMETHOXY-1 2 3 4-TETRAHYDROISOQUI&

91092-92-1
22 suppliers
$91.29/1g

223388-20-3
16 suppliers
$45.00/100mg

References