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1,3-Dimethylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione synthesis

6synthesis methods
2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-(2-propyn-1-ylamino)-

105556-09-0
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1,3-Dimethylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione

24410-25-1
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Yield:24410-25-1 89%

Reaction Conditions:

with silver hexafluoroantimonate in dimethyl sulfoxide at 110; for 1 h;regioselective reaction;

References:

Majumdar;Nandi, Raj Kumar;Ganai, Sintu;Taher, Abu [Synlett,2011,# 1,art. no. G28010ST,p. 116 - 120] Location in patent:supporting information; experimental part