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25709-80-2

4'-Bromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one synthesis

1synthesis methods
2321-07-5 Synthesis
Fluorescein

2321-07-5
358 suppliers
$6.00/25g

4'-Bromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one

25709-80-2
2 suppliers
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Yield:25709-80-2 32%

Reaction Conditions:

with N-Bromosuccinimide in methanol at 0 - 20; for 2 h;

References:

Busse, Madleen;Marciniszyn, Jaroslaw P.;Ferstl, Simone;Kimm, Melanie A.;Pfeiffer, Franz;Gulder, Tanja [Chemistry - A European Journal,2021,vol. 27,# 14,p. 4561 - 4566] Location in patent:supporting information