6-CHLORO-3,5-DIOXO HEXANIC ACID, 1,1-DIMETHYL ETHYL ESTER synthesis
1synthesis methods
- Product Name:6-CHLORO-3,5-DIOXO HEXANIC ACID, 1,1-DIMETHYL ETHYL ESTER
- CAS Number:276249-18-4
- Molecular formula:C10H15ClO4
- Molecular Weight:234.68
Yield:276249-18-4 97%
Reaction Conditions:
for 2.5 h;Product distribution / selectivity;Reflux;
Steps:
2b
A mixture of compound of formula (2) (5.2 g, 19.8 mmol), prepared according to example 1, and tert-butanol (52 mL, 0.55 mol) was stirred at reflux for 2.5 h. The resulting reaction mixture was concentrated under reduced pressure to provide compound of formula (3) (4.5 g, 97 %).
References:
WO2012/130919,2012,A1 Location in patent:Page/Page column 24