2-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]quinazolin-4(1H)-one synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: ammonium acetate / ethanol / 0.42 h / 100 °C / Microwave irradiation; Sealed tube
2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 100 °C / Inert atmosphere

References:

Deiana, Marco;Chand, Karam;Jamroskovic, Jan;Obi, Ikenna;Chorell, Erik;Sabouri, Nasim [Angewandte Chemie - International Edition,2020,vol. 59,# 2,p. 896 - 902][Angew. Chem.,2020,vol. 132,# 2,p. 906 - 912,7]