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29400-84-8

4-chloro-3-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE) synthesis

3synthesis methods
637022-63-0 Synthesis
4-Chloro-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester

637022-63-0
9 suppliers
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Yield:29400-84-8 97%

Reaction Conditions:

with lithium hydroxide in tetrahydrofuran;methanol at 80; for 3 h;

References:

Skinner, Philip J.;Cherrier, Martin C.;Webb, Peter J.;Shin, Young-Jun;Gharbaoui, Tawfik;Lindstrom, Andrew;Hong, Vu;Tamura, Susan Y.;Dang, Huong T.;Pride, Cameron C.;Chen, Ruoping;Richman, Jeremy G.;Connolly, Daniel T.;Semple, Graeme [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 20,p. 5620 - 5623]