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(2E)-1,3-bis(3-bromophenyl)prop-2-en-1-one synthesis

1synthesis methods
3132-99-8 Synthesis
3-Bromobenzaldehyde

3132-99-8
481 suppliers
$5.00/10g

2142-63-4 Synthesis
3'-Bromoacetophenone

2142-63-4
392 suppliers
$5.00/10g

(2E)-1,3-bis(3-bromophenyl)prop-2-en-1-one

103953-98-6
5 suppliers
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Yield:103953-98-6 91%

Reaction Conditions:

with sodium hydroxide in ethanol;water at 23; for 16 h;

References:

Scheuermann, Thomas H.;Stroud, Daniel;Sleet, Christopher E.;Bayeh, Liela;Shokri, Cameron;Wang, Hanzhi;Caldwell, Charles G.;Longgood, Jamie;MacMillan, John B.;Bruick, Richard K.;Gardner, Kevin H.;Tambar, Uttam K. [Journal of Medicinal Chemistry,2015,vol. 58,# 15,p. 5930 - 5941] Location in patent:supporting information