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(2R)-2-(1-Methylethyl)oxirane synthesis

5synthesis methods
-

Yield:82378-47-0 99%

Reaction Conditions:

with potassium hydroxide in neat (no solvent) at -78 - 60; under 45.0045 Torr;

References:

Hattori, Hiromu;Roesslein, Joel;Caspers, Patrick;Zerbe, Katja;Miyatake-Ondozabal, Hideki;Ritz, Daniel;Rueedi, Georg;Gademann, Karl [Angewandte Chemie - International Edition,2018,vol. 57,# 34,p. 11020 - 11024][Angew. Chem.,2018,vol. 57,# 34,p. 11020 - 11024,5] Location in patent:supporting information