ChemicalBook CAS DataBase List (2R)-2-hydroxyoctanoic acid

(2R)-2-hydroxyoctanoic acid synthesis

8synthesis methods

Product Name:(2R)-2-hydroxyoctanoic acid
CAS Number:30117-44-3
Molecular formula:C8H16O3
Molecular Weight:160.21

617-73-2 Synthesis

617-73-2
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30117-44-3
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Yield:99 % ee

Reaction Conditions:

with fatty acid photodecarboxylase from Chlorella variabilis NC₆₄A/G₄₆₂Y mutant in aq. phosphate buffer;dimethyl sulfoxide at 20; pH=8.5; for 12 h;Kinetics;Irradiation;Resolution of racemate;Enzymatic reaction;enantioselective reaction;Reagent/catalyst;

References:

Xu, Jian;Hu, Yujing;Fan, Jiajie;Arkin, Mamatjan;Li, Danyang;Peng, Yongzhen;Xu, Weihua;Lin, Xianfu;Wu, Qi [Angewandte Chemie - International Edition,2019,vol. 58,# 25,p. 8474 - 8478][Angew. Chem.,2019,vol. 131,p. 8562 - 8566,5] Location in patent:supporting information