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(2R,3S)-3-PHENYLSERINE synthesis

2synthesis methods
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Yield:91.1 % de

Reaction Conditions:

with 4-morpholineethanesulfonic acid;pyridoxal 5'-phosphate;D-threonine aldolase from Delftia sp. RIT313 cloned and expressed in Escherichia coli BL21;sodium hydroxide;manganese(ll) chloride in water;acetonitrile at 10; pH=6; for 12 h;Enzymatic reaction;stereoselective reaction;Aldol Addition;

References:

Chen, Qijia;Chen, Xi;Cui, Yunfeng;Ren, Jie;Lu, Wei;Feng, Jinhui;Wu, Qiaqing;Zhu, Dunming [Catalysis science and technology,2017,vol. 7,# 24,p. 5964 - 5973]