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(2R)-N-Methyl-2-PyrrolidinecarboxaMide synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 7 h / 0 - 25 °C
2: palladium 10% on activated carbon; hydrogen / methanol / 760.05 Torr

References:

EP2842946,2015,A1

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