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(2S,3E)-4-Bromo-1-(4-fluorophenoxy)-3-buten-2-ol synthesis

5synthesis methods
-

Yield:524714-06-5 81%

Reaction Conditions:

with lithium aluminium tetrahydride;aluminium trichloride in diethyl ether; for 0.5 h;Heating;

References:

Guilford, William J.;Bauman, John G.;Skuballa, Werner;Bauer, Shawn;Wei, Guo Ping;Davey, David;Schaefer, Caralee;Mallari, Cornell;Terkelsen, Jennifer;Tseng, Jih-Lie;Shen, Jun;Subramanyam, Babu;Schottelius, Arndt J.;Parkinson, John F. [Journal of Medicinal Chemistry,2004,vol. 47,# 8,p. 2157 - 2165]