3-(1,8-NAPHTHYRIDIN-2-YL)PROPAN-1-OL synthesis
1synthesis methods
- Product Name:3-(1,8-NAPHTHYRIDIN-2-YL)PROPAN-1-OL
- CAS Number:870089-46-6
- Molecular formula:C11H12N2O
- Molecular Weight:188.23
Yield:870089-46-6 33%
Reaction Conditions:
with L-proline in ethanol; for 24 h;Reflux;Friedlaender synthesis;
References:
Rerat, Vincent;Dive, Georges;Cordi, Alex A.;Tucker, Gordon C.;Bareille, Reine;Amédée, Jo?lle;Bordenave, Laurence;Marchand-Brynaert, Jacqueline [Journal of Medicinal Chemistry,2009,vol. 52,# 22,p. 7029 - 7043] Location in patent:supporting information; experimental part