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131417-49-7

3-(1-acetylpiperidin-4-yl)propanoic acid synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 93 percent / CH2Cl2 / 0.17 h / Ambient temperature
2: H2, acetic acid / PtO2 / 40 - 45 °C / 760 Torr
3: 1 h / Heating
4: 93 percent / aq. KOH / methanol / 1 h / Ambient temperature

References:

Ishihara;Miyamoto;Nakayama;Goto [Chemical and Pharmaceutical Bulletin,1993,vol. 41,# 3,p. 529 - 538]