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ChemicalBook CAS DataBase List 3-(1-adamantyl)-2-propynoic acid

3-(1-adamantyl)-2-propynoic acid synthesis

4synthesis methods
3-(1-adamantyl)-2-propynoic acid

106386-45-2
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: AlBr3 / -65 °C
2: potassium hydroxide / bis-(2-hydroxy-ethyl) ether / Heating
3: 1.) methyllithium / 1.) diethyl ether, 2.) -78 deg C

References:

Zhang, Biliang;Breslow, Ronald [Journal of the American Chemical Society,1997,vol. 119,# 7,p. 1676 - 1681]