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3-(2-fluorophenyl)-4H-chroMen-4-one synthesis

2synthesis methods
49619-82-1 Synthesis
3-BROMOCHROMONE

49619-82-1
132 suppliers
$15.00/250mg

1993-03-9 Synthesis
2-Fluorophenylboronic acid

1993-03-9
349 suppliers
$8.00/1g

3-(2-fluorophenyl)-4H-chroMen-4-one

1143863-58-4
1 suppliers
inquiry

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Yield:1143863-58-4 74%

Reaction Conditions:

with bis-triphenylphosphine-palladium(II) chloride;potassium carbonate in tetrahydrofuran; for 20 h;Reflux;Inert atmosphere;Hoshino-Suzuki-Miyaura coupling;

References:

Nibbs, Antoinette E.;Baize, Amanda-Lauren;Herter, Rachel M.;Scheidt, Karl A. [Organic Letters,2009,vol. 11,# 17,p. 4010 - 4013] Location in patent:supporting information; experimental part