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3-(2-Methoxy-phenoxy)-propionic acid synthesis
- Product Name:3-(2-Methoxy-phenoxy)-propionic acid
- CAS Number:20370-80-3
- Molecular formula:C10H12O4
- Molecular Weight:196.2
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70786-42-4
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20370-80-3
28 suppliers
$29.00/100mg
Yield:20370-80-3 90%
Reaction Conditions:
with hydrogenchloride in water at 80 - 90;
Steps:
General experimental procedure for the synthesis of 3-aryloxypropanoic acids (3a-3o)
General procedure: Mixture of 3-aryloxypropane nitrile (2a-2o) (2 mmol) and conc. HCl (1-2 mL) is heated at 80-90 °C for about 1- 2 h (after monitoring the reaction completion by TLC). Cooled the reaction mass and added ice water to obtain solid 3-aryloxypropanoic acid (3a-3o) as solids which is filtered and dried to be taken up for the subsequent step.
References:
Begum, Ayisha F.;Balasubramanian, Kalpattu K.;Shanmugasundaram, Bhagavathy [Tetrahedron Letters,2021,vol. 82,art. no. 153372] Location in patent:supporting information
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590-92-1
239 suppliers
$10.00/1g
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90-05-1
754 suppliers
$5.00/1g
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20370-80-3
28 suppliers
$29.00/100mg
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57-57-8
164 suppliers
$24.73/250mgs:
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90-05-1
754 suppliers
$5.00/1g
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20370-80-3
28 suppliers
$29.00/100mg

90-05-1
754 suppliers
$5.00/1g
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20370-80-3
28 suppliers
$29.00/100mg