3-[(2-methoxyphenyl)methoxy]benzaldehyde synthesis
- Product Name:3-[(2-methoxyphenyl)methoxy]benzaldehyde
- CAS Number:123926-42-1
- Molecular formula:C15H14O3
- Molecular Weight:242.27
Yield:123926-42-1 76.7%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 80; for 3 h;
Steps:
18.1 (1) 3 - (2 - methoxy animal pen oxygen radical) benzaldehyde preparation
The 3 - hydroxybenzaldehyde (0.50 g, 4 . 14 mmol) dissolved in 8 ml DMF in, adding 2 - methoxy animal pen bromine (1.00 g, 4 . 97 mmol), potassium carbonate (0.86 g, 6 . 22 mmol), 80 °C reaction 3 hours, adding 15 ml distilled water, extracted with ethyl acetate twice (2 × 20 ml), then saturated sodium chloride solution for washing 1 time, dried with anhydrous sodium sulfate. Concentrated, column chromatography, eluting agent is petroleum ether: ethyl acetate=3:1, to obtain white solid 0.76 g, yield 76.7%
References:
CN107151220,2017,A Location in patent:Paragraph 0343; 0344; 0345; 0346; 0347
