3-(2-naphthyl)-5-(trifluoromethyl)-1H-pyrazole synthesis
- Product Name:3-(2-naphthyl)-5-(trifluoromethyl)-1H-pyrazole
- CAS Number:376373-29-4
- Molecular formula:C14H9F3N2
- Molecular Weight:262.23
Yield:376373-29-4 91%
Reaction Conditions:
with 1,8-diazabicyclo[5.4.0]undec-7-ene;toluene-4-sulfonic acid hydrazide in toluene at 60; for 6 h;regioselective reaction;
References:
Zhu, Chuanle;Zeng, Hao;Liu, Chi;Cai, Yingying;Fang, Xiaojie;Jiang, Huanfeng [Organic Letters,2020,vol. 22,# 3,p. 809 - 813] Location in patent:supporting information
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