3-((2R)PYRROLIDIN-2-YL)-5-FLUOROPYRIDINE synthesis
- Product Name:3-((2R)PYRROLIDIN-2-YL)-5-FLUOROPYRIDINE
- CAS Number:1212928-22-7
- Molecular formula:C9H11FN2
- Molecular Weight:166.2
407-20-5
339 suppliers
$10.00/1g
1212928-22-7
8 suppliers
inquiry
Yield:-
Steps:
Multi-step reaction with 4 steps
1.1: isopropylmagnesium chloride / tetrahydrofuran / 2 h / 0 - 20 °C
1.2: 16 h / 20 °C
2.1: (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole; dimethylsulfide borane complex / tetrahydrofuran / 20 h / 20 °C
3.1: triethylamine / dichloromethane / 16 h / 20 °C
4.1: ammonium hydroxide / methanol / 4 h / 70 °C
References:
CN108101820,2018,A