3,3',5-TRIFLUOROBENZHYDROL synthesis

3synthesis methods

Product Name:3,3',5-TRIFLUOROBENZHYDROL
CAS Number:844683-66-5
Molecular formula:C13H9F3O
Molecular Weight:238.21

461-96-1 Synthesis

461-96-1
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$6.00/10g

456-48-4 Synthesis

456-48-4
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$9.00/25g

844683-66-5
15 suppliers
$809.00/1g

951885-79-3
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Yield:844683-66-5 62%

Reaction Conditions:

Stage #1: 3,5-difluorobromobenzenewith iodine;magnesium in tetrahydrofuran;Reflux;
Stage #2: 3-Fluorobenzaldehyde in tetrahydrofuran at 0 - 20;Grignard reaction;

References:

Nolte, Christoph;Mayr, Herbert [European Journal of Organic Chemistry,2010,# 8,p. 1435 - 1439] Location in patent:supporting information; experimental part

Benzenemethanol, 3,5-difluoro-α-(3-fluorophenyl)-, 1-(4-methylbenzenesulfonate)

1224964-63-9
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844683-66-5
15 suppliers
$809.00/1g

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Benzenemethanol, 3,5-difluoro-α-(3-fluorophenyl)-, 1-methanesulfonate

1224964-65-1
0 suppliers
inquiry

844683-66-5
15 suppliers
$809.00/1g

References