3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE synthesis
- Product Name:3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE
- CAS Number:168084-95-5
- Molecular formula:C14H11ClO2
- Molecular Weight:246.69
99-06-9
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766-80-3
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$7.00/5g
168084-95-5
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$45.00/50mg
Yield:168084-95-5 74%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 80; for 3 h;
Steps:
8.1 (1) 3 - (3 - chloryl) benzaldehyde preparation
The 3 - hydroxybenzaldehyde (1.0 g, 8.2 mmol) dissolved in 15 mLDMF in, adding 3 - chlorine animal pen bromine (1.84 g, 9.0 mmol), potassium carbonate (1.35 g, 9.8 mmol), 80 °C reaction 3 hours, adding 15 ml distilled water, extracted with ethyl acetate twice (2 × 20 ml), then saturated sodium chloride solution for washing 1 time, dried with anhydrous sodium sulfate. Concentrated, column chromatography, eluting agent is petroleum ether: ethyl acetate=3:1, shall be transparent oil to 1.5 g, yield 74%.
References:
CN107151220,2017,A Location in patent:Paragraph 0178; 0179; 0180; 0181; 0182
100-83-4
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766-80-3
221 suppliers
$7.00/5g
168084-95-5
20 suppliers
$45.00/50mg