![](/CAS/GIF/168084-95-5.gif)
3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE synthesis
- Product Name:3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE
- CAS Number:168084-95-5
- Molecular formula:C14H11ClO2
- Molecular Weight:246.69
![3-Hydroxybenzoic acid](/CAS/GIF/99-06-9.gif)
99-06-9
481 suppliers
$5.00/25g
![3-Chlorobenzyl bromide](/CAS/GIF/766-80-3.gif)
766-80-3
220 suppliers
$7.00/5g
![3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE](/CAS/GIF/168084-95-5.gif)
168084-95-5
18 suppliers
$45.00/50mg
Yield:168084-95-5 74%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 80; for 3 h;
Steps:
8.1 (1) 3 - (3 - chloryl) benzaldehyde preparation
The 3 - hydroxybenzaldehyde (1.0 g, 8.2 mmol) dissolved in 15 mLDMF in, adding 3 - chlorine animal pen bromine (1.84 g, 9.0 mmol), potassium carbonate (1.35 g, 9.8 mmol), 80 °C reaction 3 hours, adding 15 ml distilled water, extracted with ethyl acetate twice (2 × 20 ml), then saturated sodium chloride solution for washing 1 time, dried with anhydrous sodium sulfate. Concentrated, column chromatography, eluting agent is petroleum ether: ethyl acetate=3:1, shall be transparent oil to 1.5 g, yield 74%.
References:
CN107151220,2017,A Location in patent:Paragraph 0178; 0179; 0180; 0181; 0182
![3-Hydroxybenzaldehyde](/CAS/GIF/100-83-4.gif)
100-83-4
618 suppliers
$5.00/10g
![3-Chlorobenzyl bromide](/CAS/GIF/766-80-3.gif)
766-80-3
220 suppliers
$7.00/5g
![3-[(3-CHLOROBENZYL)OXY]BENZALDEHYDE](/CAS/GIF/168084-95-5.gif)
168084-95-5
18 suppliers
$45.00/50mg