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3,3-dichloro-2-Piperidinone synthesis

4synthesis methods
-

Yield:41419-12-9 85%

Reaction Conditions:

with phosphorus pentachloride in chloroform;Reflux;

References:

Qiao, Jennifer X.;Cheney, Daniel L.;Alexander, Richard S.;Smallwood, Angela M.;King, Sarah R.;He, Kan;Rendina, Alan R.;Luettgen, Joseph M.;Knabb, Robert M.;Wexler, Ruth R.;Lam, Patrick Y.S. [Bioorganic and Medicinal Chemistry Letters,2008,vol. 18,# 14,p. 4118 - 4123] Location in patent:scheme or table