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3-(3-hydroxypropyl)benzonitrile synthesis

7synthesis methods
-

Yield:83101-13-7 75%

Reaction Conditions:

Stage #1: 3-allyl benzonitrilewith borane in tetrahydrofuran at 0; for 1 h;
Stage #2: with sodium hydroxide;dihydrogen peroxide in tetrahydrofuran at 0; for 0.666667 h;

References:

Lee, B. C.;Choe, Y. S.;Lee, K. H.;Kim, B.-T.;Chi, D. Y. [Journal of labelled compounds and radiopharmaceuticals,2001,vol. 44,p. S404 - S406]