ChemicalBook CAS DataBase List 3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE

3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE synthesis

8synthesis methods

Product Name:3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE
CAS Number:78583-81-0
Molecular formula:C9H8ClN3
Molecular Weight:193.63

74-11-3
561 suppliers
$5.00/1g

78583-81-0
124 suppliers
$24.00/1g

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: sulfuric acid / ethanol / 12 h / Reflux
2.1: sodium hydride / toluene / 0.5 h / 0 °C
2.2: 12 h / 100 °C
3.1: hydrazine hydrate / ethanol / 12 h / Reflux

References:

NORGINE B.V.;BAKTHAVATCHALAM, Rajagopal;BASU, Manas Kumar;BEHERA, Ajit Kumar;VENKATESHAPPA, Chandregowda;HEWSON, Christopher Alexander;KADNUR, Sanjay Venkatachalapathi;KALINDJIAN, Sarkis Barret;KULKARNI, Bheemashankar;SAXENA, Rohit;SURESH, Juluri;VISWANATHAN, Vellarkad;ZAINUDDIN, Mohd;DHARSHINIS, Akila Parvathy;KRISTAM, Rajenda WO2015/97122, 2015, A1

4640-66-8 Synthesis