3,4-DIAMINO-BENZAMIDE synthesis
- Product Name:3,4-DIAMINO-BENZAMIDE
- CAS Number:7005-37-0
- Molecular formula:C7H9N3O
- Molecular Weight:151.17
17626-40-3
200 suppliers
$10.00/1g
7005-37-0
15 suppliers
$261.00/500mg
Yield:7005-37-0 70%
Reaction Conditions:
with sulfuric acid at 20;
Steps:
(i) 3,4-Diaminobenzamide (11)
A solution of 3,4-diaminobenzonitrile (1.0 g, 7.51 mmol) in concentrated sulfuric acid (20 ml_) was stirred at room temperature overnight. Water (100 ml_) was added and the resulting mixture was adjusted to pH 10 with 4 M aqueous NaOH and extracted with EtOAc (100 ml_ c 3). The combined organic extracts were concentrated under reduced pressure to give the title compound 11 (800 mg, 70%) as a light yellow solid. LCMS-A (ES-API): rt 0.31 min, m/z 152.0 [M+H]+.
References:
WO2021/9362,2021,A1 Location in patent:Page/Page column 78
41263-65-4
17 suppliers
$64.00/250mg
7005-37-0
15 suppliers
$261.00/500mg
1588-83-6
276 suppliers
$6.00/5g
7005-37-0
15 suppliers
$261.00/500mg